Alternative sampling specimens for the molecular detection of mpox (formerly monkeypox) virusArticle Published on 2023-02-012023-06-09 Journal: Journal of Clinical Virology [Category] Fulltext, 원숭이두창, [키워드] Blood Diagnosis Laboratory Monkeypox PCR plasma. Saliva sensitivity specimens throat swab [DOI] 10.1016/j.jcv.2022.105372 PMC 바로가기
Clinical and virological features of first human monkeypox cases in GermanyArticle Published on 2023-02-012023-06-14 Journal: Infection [Category] Fulltext, 조류인플루엔자, [키워드] Blood Efflorescence Germany HIV Monkeypox Semen Skin lesion. [DOI] 10.1007/s15010-022-01874-z PMC 바로가기
Cross-talk between red blood cells and plasma influences blood flow and omics phenotypes in severe COVID-19Article Published on 2022-12-202023-07-11 Journal: eLife [Category] COVID19(2023년), [키워드] Blood Cell Biology COVID-19 Human Microfluidics omics physics of living systems red blood cells. [DOI] 10.7554/eLife.81316 PMC 바로가기
Changes of Routine Hematological Parameters in COVID-19 Patients: Correlation with Imaging Findings, RT-PCR and OutcomeOriginal Article Published on 2022-12-152022-10-29 Journal: Iranian Journal of Pathology [Category] COVID-19, [키워드] Admission age analyses Biochemical parameters Blood change Chest chest imaging Chest tomography Concentration Coronavirus disease 2019 correlated correlation correlations COVID-19 COVID-19 case COVID-19 patient Critical CRP CT-scan demonstrated diagnosed Diagnosis during admission enrolled evaluated expired group hematologic hematology hemoglobin Hospitalized imaging investigated Laboratory LDH less leukocyte lung lung involvement Lymphocytes neutrophil no increase outcome parameter parameters participant Patient patients Platelet platelets count Prognostic value raise researcher respiratory viral routine RT-PCR severity Severity of disease the disease tomography Tomography scanners upper respiratory Viral load WBC were measured White blood cells [DOI] 10.30699/IJP.2021.533645.2675 PMC 바로가기 [Article Type] Original Article
Current trends in COVID-19 diagnosis and its new variants in physiological fluids: Surface antigens, antibodies, nucleic acids, and RNA sequencingReview article Published on 2022-12-012022-10-05 Journal: TrAC Trends in Analytical Chemistry [Category] 바이오마커, 변종, 진단, 치료기술, [키워드] addressed antibodies antibody Antigen antigens Beta Biomarker biosensors Blood body fluid circulation clustered regularly interspaced short palindromic repeats COVID-19 COVID-19 diagnosis COVID-19 virus diagnosis CRISPR Critical current Delta Detection sensitivity diagnostic early stage ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Gamma Infection isothermal amplification lateral flow immunoassay LFIA limit Loop-mediated isothermal amplification microarray analysis Microarray assays Mutation nucleic acid nucleic acids omicron outbreak overcome palindromic repeat physiological provide Rapid reduce reverse transcriptase-polymerase chain reaction reverse transcription RNA sequencing RT-LAMP RT-PCR Saliva SARS-CoV-2 Semen specificity Spread surface Urine variant variants virus viruses [DOI] 10.1016/j.trac.2022.116750 [Article Type] Review article
Clinical features and high-resolution chest computerized tomography findings of children infected by the B.1.617.2 variant of coronavirus disease 2019Article Published on 2022-12-012022-11-16 Journal: Annals of Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] absence age analysed analyses B.1.617.2 B.1.617.2 (Delta) variant biochemical Blood Cell Chest Chest CT chest. children China clinical clinical symptom Clinical symptoms collected Computerized tomography Concentration consolidation coronavirus disease corpuscular correlated correlation cough COVID-19 CT CT finding Delta Diagnosis Disease diagnosis disease stage distribution elevated Factor feature Fever Follow-up ground-glass opacity group Haemoglobin High-resolution imaging Infection Laboratory Laboratory tests lymphocyte males Mild monocyte Nanjing no difference pathological change Patient percentage pharyngeal Platelet regression analysis serum alkaline phosphatase significant effect Stage stages statistically significant Subtypes Symptom Symptoms the disease variant Volume [DOI] 10.1080/07853890.2022.2114608 PMC 바로가기
Sex-biased expression of the TLR7 gene in severe COVID-19 patients: Insights from transcriptomics and epigenomicsArticle Published on 2022-12-012022-11-16 Journal: Environmental research [Category] 유전자 메커니즘, [키워드] acute phase analyzed Blood Cohort coronavirus disease COVID-19 COVID-19 patient CpG DNA DNA methylation dose downregulated embryogenesis epidemiological data epigenomic epigenomics Evidence expression female females gene product Genetic variation Genome-wide association studies Host inactivation incidence incidence of COVID-19 independent insight long-COVID-19 male males Methylation n-Counter. nasal patients Post-infection RNAseq Saliva Severe case severe COVID-19 severity Sex significantly higher stratified suggested timepoint TLR7 TLR7 gene transcriptomics with COVID-19 [DOI] 10.1016/j.envres.2022.114288 PMC 바로가기
Preclinical assessment and randomized Phase I study of CT-P63, a broadly neutralizing antibody targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Article Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 비임상, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome Beta Blood caused clinically Concentration coronavirus COVID-19 creatine phosphokinase CT-P63 deaths declining Delta demonstrated detectable dose double-blind evaluated groups healthy volunteer Immunity in vitro in vivo Infection Infectious virus lung monoclonal monoclonal antibody morbidity and mortality mutated variant Neutralizing Neutralizing activity neutralizing antibody neutralizing antibody. omicron pandemic parallel-group participant peaked phase Placebo placebo-controlled Preclinical prevalent Prophylactic Randomized reduced respiratory tract Safe SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants of concern Serious Adverse Events significantly single ascending dose study drug TEAE titre Tolerability Transgenic mouse treated Treatment treatment-emergent adverse event vaccination variants variants of SARS-CoV-2 wild-type [DOI] 10.1080/22221751.2022.2117094 PMC 바로가기
Saliva as a Potential Specimen to Monitor IL-6, TNF-α and IL-10 in COVID-19 PatientsArticle Published on 2022-12-012022-11-15 Journal: Inflammation [Category] COVID19(2023년), SARS, 치료기술, [키워드] alleviate Blood blood specimen Clinical prognosis collected comparable COVID-19 COVID-19 patients cycle threshold detectable elevated elicited enrolled expressed expression human saliva IL-10 IL-10. IL-6 inclusion criteria Infection Inflammation Inflammation. Inflammatory Inflammatory cytokine inflammatory gene Lung injury marker MINI Mortality Patient pilot study Potential protocols Qiagen RNA RT-PCR Saliva SARS-CoV-2 severe cases specimen subject the mean TNF-α were assessed [DOI] 10.1007/s10753-022-01698-x PMC 바로가기
Immunogenicity and protectivity of intranasally delivered vector-based heterologous prime-boost COVID-19 vaccine Sputnik V in mice and non-human primatesArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] accompanied Blood clinical investigation Coverage COVID-19 COVID-19 pandemic COVID-19 vaccine cytokine release Diseases effective effort elicit Gam-COVID-Vac Health heterologous prime-boost IgA antibody IgG immune response Immunity immunization immunogenic immunogenicity Infection intranasal intranasal vaccine. intranasally K18-hACE2 transgenic mice less lung immunopathology mice mononuclear cell Mortality mucosal nasal mucosa neutralizing antibody non-human primate pandemic Peripheral blood Prevent proliferation protective immunity provided revaccination robust SARS-CoV-2 SARS-COV-2 infection SARSCoV-2 serum Sputnik V systemic and local the vaccine Transmission vaccination Vaccination strategy Vaccine vaccine candidate variants of concern virus virus infection virus spread [DOI] 10.1080/22221751.2022.2119169 PMC 바로가기